More than 100 Post Office branches and hundreds of head office jobs are at risk in a radical shake-up at the company, according to the BBC.
As part of this plan, 115 loss-making branches, entirely owned by the Post Office, could be closed.
The Post Office is exploring options including alternative franchise agreements in which another operator or third party could take over the branches instead.
These sites employ around 1,000 employees. Furthermore, hundreds of jobs are threatened at the group's headquarters.
New Post Office chairman Nigel Railton will brief staff on Wednesday on the results of a study launched earlier this year.
The former Camelot boss was named interim chairman of the Post Office following the dismissal of his predecessor Henry Staunton in January.
The objective of this revision is to give the Post Office a more solid financial basis.
The embattled organization is currently the subject of a long-running investigation into the Horizon IT scandal, in which hundreds of subpostmasters were wrongly prosecuted after faulty software made it appear that Money was missing from their accounts.
Railton has previously told the Post Office inquiry that a new deal was needed for subpostmasters, to put them at the center of the business.
The strategic review aims to fundamentally change the way the Post Office operates.
The company has 11,500 post offices across the UK, most of which are franchises.
Of these, 115 are Crown post offices located in town centers and staffed by Post Office employees.
Earlier this month, Postmaster General Gareth Thomas said the organization was at a critical juncture and the government had already commissioned its own study into what the Post Office should look like in the future.
Business Secretary Jonathan Reynolds told the inquiry on Monday he did not believe subpostmasters were receiving appropriate remuneration for the volume of business they conducted.
He suggested that Post Office branches could fill the gap left by High Street bank branch closures.