The 2024 NFL regular season will open on Thursday, September 5, with the Kansas City Chiefs hosting the Baltimore Ravens in the annual 2024 NFL Kickoff Game. Both teams are among the top contenders in the 2025 Super Bowl odds, with the Chiefs being the favorites to win the Lombardi Trophy for a third consecutive year. Kansas City is favored by three points in the NFL odds for Week 1, but Lamar Jackson and the Ravens will be eager to get revenge after losing to the Chiefs in last year's AFC Championship Game. Other NFL matchups of interest for NFL score predictors include the Eagles (-1.5) vs. Packers in Sao Paulo, Brazil, and the Jets vs. 49ers (-5.5) on Monday Night Football.
We'll give you NFL score predictions for all 16 games in Week 1 to help you with your NFL spread picks, over/under, NFL parlays and NFL Survivor strategies. Which NFL games in Week 1 will be blowout wins and which will see lesser teams win? Before making any Week 1 NFL picks, be sure to check out SportsLine expert Eric Cohen's accurate score predictions.
Cohen, SportsLine's NFL expert and host of Friday's NFL Prop Show on SportsLine's YouTube page, will be rating every NFL game in Week 1 and providing score predictions and analysis for each matchup. Cohen earned profits for bettors last season with his NFL predictions, going 39-28. Cohen's accurate score predictions were a hit on social media last year, and he also got the right score in the playoffs, when Kansas City upset Buffalo, 27-24, in the AFC Divisional Round. Anyone who followed Cohen's NFL predictions has earned a profit. Cohen's accurate NFL score predictions for Week 1 can only be found on SportsLine.
NFL Week 1 Top Picks
Cohen, who watched all 16 games in the NFL's opening weekend, highly rates the Indianapolis Colts' 29-26 win over the Houston Texans as one of the biggest upsets at home in Week 1. The Colts are expected to have one of the best rushing attacks in the league, thanks to an above-average offensive line and a dominant player at the running back position in 2021 NFL rushing champion Jonathan Taylor. Taylor has only played in 10 games in 2023 (seven as a starter), but still rushed 169 times for 741 yards and seven touchdowns. He also caught 19 passes for 153 yards and one score.
Perhaps the biggest reason for Cohen's optimism about the Colts is second-year quarterback Anthony Richardson. The former Florida star is one of the most athletic quarterbacks in NFL history, but an injury ended his rookie year after just four games. If Richardson makes a big leap in Year 2, the Colts could be a threat to win the AFC South. Get his Week 1 Football Score predictions at SportsLine.
How to make Week 1 NFL score predictions
Additionally, Cohen expects the AFC championship favorite to crush their Week 1 opponent by at least three touchdowns, and predicting this outcome will be key to winning NFL games in Week 1, only at SportsLine.
Who will win each NFL Week 1 game, and which AFC teams will dominate their opponents? Visit SportsLine now to get NFL Week 1 score predictions from NFL expert Eric Cohen, who finished 39-28 last season.
