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The NFL will expand its global footprint as the second game of the 2024-25 season will be played in Sao Paulo, Brazil, between the Green Bay Packers and Philadelphia Eagles. With two marquee franchises that made the playoffs last season and have bright futures, the league is promoting its best to international audiences. Friday night's game will feature star quarterbacks Jordan Love and Jalen Hurts, who rank among the top 10 highest-paid players in the league. Which stars should you root for in your NFL picks and NFL score predictions? The Eagles are 2.5-point favorites in our Week 1 NFL odds with a total of 48.5. Before making any Week 1 NFL picks, be sure to check out SportsLine expert Eric Cohen's accurate score predictions.
Cohen, SportsLine's NFL expert and host of Friday's NFL Prop Show on SportsLine's YouTube page, will be rating every NFL game in Week 1 and providing score predictions and analysis for each matchup. Cohen earned profits for bettors last season with his NFL predictions, going 39-28. Cohen's accurate score predictions were a hit on social media last year, and he also got the right score in the playoffs, when Kansas City upset Buffalo, 27-24, in the AFC Divisional Round. Anyone who followed Cohen's NFL predictions has earned a profit. Cohen's accurate NFL score predictions for Week 1 can only be found on SportsLine.
NFL Week 1 Top Picks
Cohen, who watched all 16 games in the NFL's opening weekend, likes to see the Indianapolis Colts beat the Houston Texans, 29-26, in one of the biggest upsets at home in Week 1. The Colts boast one of the NFL's best rushing attacks with quarterback Anthony Richardson and running back Jonathan Taylor. Richardson appeared in just four games in his rookie season, scoring four points in that time. He and Taylor played together less than half the time after the running back returned from a multi-game contract extension refusal.
In Week 18 against Houston, the dynamic running back ran 30 times for 188 yards, but the Colts lost a close game to the Texans, costing them the division title and a playoff berth. Taylor scored in each of his final five games last season and should be a tough player for opponents to stop. Houston will be looking to take the next step after their amazing 2023 season, but Cohen believes Indianapolis will pull out a win in what should be one of the most entertaining Week 1 gameplay matches. Check out SportsLine for his Week 1 football score predictions.
How to make NFL Week 1 score predictions
Additionally, Cohen expects the AFC championship favorite to crush their Week 1 opponent by at least three touchdowns, and predicting this outcome will be key to winning NFL games in Week 1, only at SportsLine.
Who will win each NFL Week 1 game, and which AFC teams will dominate their opponents? Visit SportsLine now to get NFL Week 1 score predictions from NFL expert Eric Cohen, who finished 39-28 last season.
