The Chicago White Sox (30-97) and San Francisco Giants (65-63) complete a three-game series on Wednesday, with the first pitch at Oracle Park scheduled for 3:45 PM ET. Break down FanDuel Sportsbook's White Sox vs. Giants odds and make your best betting predictions and forecasts with MLB experts.
Season series: Giants lead 2-0
The White Sox are looking to avoid an interleague series winning streak with the under (7.5) winning after losing 4-1 on Tuesday as a +212 underdog. The Giants have outshot the Chicago White Sox 9-4 in the first two games of the series, and Chicago's offense has been limited to just five runs over their past four games for an average of 1.25 runs per game (RPG). It's no surprise that the under is 3-0-1 in that span.
The Giants have won three straight games to move above .500, allowing just eight points and averaging 1.6 rebounds in their last five games. Like Chicago, the under is 3-0, 1 draw and 1 loss in San Francisco's last four games.
Chicago enters the game with a 12-53 record on the road and a league-worst run differential of minus-263. The Chicago White Sox are also MLB-worst with a 10-29 record in interleague play.
San Francisco is 38-27 at home and 17-19 against the American League.
White Sox vs Giants predicted starting lineup
LHP Garrett Crochet vs. RHP Logan Webb
Crochette (6-9, 3.61 ERA) is making his 26th start and has a 1.07 WHIP, 2.2 BB/9 and 12.7 K/9 in 124 2/3 innings.
Last start: Friday's 5-4 win against the Houston Astros, no win/loss, 4 innings, 1 run, 4 hits, 0 walks, 9 strikeouts. 2024 road record: 2-3, 3.91 ERA (53 innings, 23 runs), 1.09 WHIP, .205 opponents batting average (OBA), 8 home runs, 11.5/9 strikeouts in 11 starts. Never faced the Giants.
Webb (11-8, 3.17 ERA) is making his 26th start and has a 1.22 WHIP, 2.2 BB/9 and 7.7 K/9 in 164 2/3 innings.
Last start: 6-0 shutout win at home against the Atlanta Braves on Thursday, 7 2/3 innings, 0 earned runs, 4H, 1BB, 7K 2024 home record: 7-3, 2.26 ERA (83 2/3 innings, 21 earned runs), 1.00 WHIP, .223 on-base percentage, 1 complete game, 3 HR, 7.0 K/9, 12 starts Career record with the White Sox: 0-2, 5.73 ERA (11 innings, 7 earned runs), 1.45 WHIP, 1BB, 9K, 2 starts
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White Sox vs Giants odds
Courtesy of FanDuel Sportsbook. For the complete list, visit the USA TODAY Sports Scores and Sports Betting Odds Hub. Lines last updated at 2:59 a.m. ET.
Money Line (ML): White Sox +190 (bet $100 to win $190) | Giants -230 (bet $230 to win $100) Run Line (RL)/Against the Spread (ATS): White Sox +1.5 (-118) | Giants -1.5 (-102) Over/Under (O/U): 7 (O: -110 | U: -110)
White Sox vs Giants predictions and forecasts
prediction
Giants 4, White Sox 2
Money Line
The Giants (-230) cost 2.3 times the potential return, which is a pretty high risk, even against a 97-loss team.
San Francisco covered the score line in the first two games of this series, winning each one by at least two points as the favorite, but there is still plenty at risk.
Pass it and focus instead on the favorites on the run line.
Against run line/spread
The Giants -1.5 (-102) are a solid bet to win, but be careful as Crochette is clearly the White Sox's best starting pitcher.
It won't be easy, but if San Francisco can get through Chicago's relief pitchers, the Giants should have enough offensive firepower to take at least a two-run lead and win the series.
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Over/Under
UNDER 7 (-110) is trending, but only play half a unit to be safe.
In the first two games of this series, the under was 1-0-1 with Chicago averaging 2.0 rebounds and San Francisco averaging 4.5 rebounds. If this final game plays out the same way, we'll likely see another under, albeit by a small margin.
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